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Molecular Cause of Breast Cancer Metastasis Discovered
Summary from multiple countries, from articles in English
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WASHINGTON - Scientists have pinpointed genetic variations that make people more likely to get hooked on cigarettes and more prone to develop lung cancer, a finding that could lead to screening tests and customized treatments for smokers trying to kick the habit. (article 2)
The discovery by three separate teams of scientists makes the strongest case so far for the biological underpinnings of nicotine addiction and sheds more light on how genetics and lifestyle habits join forces to cause cancer. (article 1)
" This is kind of a double whammy gene said Christopher Amos, a professor of epidemiology at the M.D. Anderson Cancer Center in Houston and author of one of the studies. (article 1)
A smoker who inherits these genetic variations from both parents has an 80 percent greater chance of lung cancer than a smoker without the variants, the researchers reported. (article 1)
Whether these gene variants represent a direct risk for lung cancerandincreased susceptibility to smoking isn't clear, according to two studies published in the April 3 edition ofNatureand one published in the April 2 online edition ofNature Genetics. (article 4)
All the researchers agree the work is a major stop forward in identifying people at risk for non-small cell lung cancer - which makes up 80% of all lung cancer cases. (article 5)
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Other stories about cancer, Lung and Smoking:
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Story keywords
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cancer, Lung, Smoking, smokers, breast |
Source articles
- Genetic Link Tied to Smoking Addiction (Washington Post, 04/03/2008, 385 words)
- Genes tied to cigarette addiction (seattletimes.nwsource.com, 04/03/2008, 704 words)
- Studies find genes that increase risk of lung cancer (boston.com, 04/03/2008, 665 words)
- Gene Variants Linked to Lung Cancer Identified (Washington Post, 04/02/2008, 640 words)
- Genetic link to smoking addiction (BBC News, 04/02/2008, 470 words)
- cell division and cancer (Nature Journals, 04/03/2008, 333 words)
- Molecular Cause of Breast Cancer Metastasis Discovered (Washington Post, 04/03/2008, 686 words)
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blaster@cs.columbia.edu
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