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Friday, July 18, 2008
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Alzheimer's drug trial 'promise'
Summary from multiple countries, from articles in English
A drug once used to treat hayfever "significantly improves" symptoms in patients with mild to moderate Alzheimer's disease, research suggests. (article 3) Now US researchers have found it can improve memory, behaviour and ability to conduct simple activities like eating in patients with dementia. (article 3) In the trial of 183 people who all had untreated mild to moderate dementia, which was carried out in Russia, half were given 20 mg of dimebon 20 three times a day while the rest were given a dummy pill. (article 3) In a smaller group of patients who continued with the trial for a further six months there was an even greater seven-point gap between those on dimebon and those on placebo. (article 3) But a new drug called Dimebon appears to stop and perhaps even reverse the symptoms of the cruel and degenerative disease, according to a new study published in the journal Lancet today. (article 2) In another first, Dimebon's effect continued for more than a year, while current Alzheimer's treatments are known to peak at three or six months and then begin to lose their effects. (article 1) Autopsies on seven patients who died of Alzheimer's during the study showed that nearly all of the sticky beta-amyloid protein thought to be dangerous had been removed. (article 4)

Other summaries about this story:
  • Summary from the United Kingdom, from articles in English (1 articles) [compare]
  • Summary from United States, from articles in English (3 articles) [compare]

  • Event tracking:
  • Track this story's development in time

  • Story keywords
    alzheimer, Dimebon, Doody, Disease, patients

    Source articles
    1. Allergy Drug Turned Alzheimer's Therapy (ABCNews, 07/17/2008, 777 words)
    2. ABC News: Drug Seems to Slow Alzheimer's Symptoms (ABCNews, 07/17/2008, 372 words)
    3. Alzheimer's drug trial 'promise' (BBC News, 07/18/2008, 238 words)
    4. Alzheimer's vaccine stopped plaque, not dementia (Washington Post, 07/16/2008, 387 words)




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